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WHAT CAUSES MALIGNANT MESOTHELIOMA?

Mesothelioma Prevention - How to Prevent Asbestos Cancer

The Truth About WHAT CAUSES MALIGNANT MESOTHELIOMA? In 3 Minutes
Malignant Mesothelioma

What Causes Malignant Mesothelioma?

Researchers have found several factors that increase a person’s risk of mesothelioma,but it’s not yet clear exactly how all of these factors might cause this cancer.

Cancers, including mesotheliomas, occur when cells in the body suffer damage to their DNA. DNA is the chemical in each of our cells that makes up our genes – the instructions for how our cells  unction. We usually look like our parents because they are the source of our DNA.

mesothelioma specialists

But DNA affects more than how we look. Some genes control when cells in the body grow, divide into new cells, and die at the right time.Changes in these genes may cause cells to grow out of control, which can lead to cancer.

Asbestos exposure is the main cause of pleural mesothelioma. When asbestos fibers are breathed in, they travel to the ends of small air passages and reach the pleura, where they can cause inflammation and scarring. This may damage cells’ DNA and cause changes that result in uncontrolled cell growth. If swallowed, these fibers can reach the abdominal lining, where they can have a role in causing peritoneal mesothelioma.

But most people exposed to asbestos, even in large amounts, do not get mesothelioma. Other factors, such as a person’s genes, may make them more likely to develop mesothelioma when exposed to asbestos. For example, researchers have found that some people who seem to be at high risk have changes in BAP1, a gene that normally helps keep cell growth under control. Other genes are probably important as well.Radiation treatments for other cancers have been linked to mesothelioma in some studies. Radiation can damage the cells’ DNA, leading to out-of-control cell growth.It is still not known if infection with the SV40 virus increases the risk of mesothelioma, or exactly how it might do so. In lab studies, researchers have found that the virus can affect certain genes that have been linked with cancer, but further research in this area is needed.

The Truth About WHAT CAUSES MALIGNANT MESOTHELIOMA? In 3 Minutes
prognosis of malignant mesothelioma

Can Malignant Mesothelioma Be Prevented?

Being exposed to asbestos is by far the biggest risk factor for mesothelioma, so the best way to reduce your risk is to limit your exposure to asbestos at home, in public buildings, and at work.People who might be exposed to high levels of asbestos at work include some miners, factory workers, insulation manufacturers and installers, railroad and automotive workers, ship builders, gas mask manufacturers, plumbers, and construction workers. If there is a chance of on-the-job exposure, such as during the renovation of old buildings, you should use all protective equipment and safety procedures designed for working around asbestos.

Older homes may have insulation containing asbestos or other materials. A knowledgeable expert can check your home to find out if there is any asbestos and whether it poses any risk of exposure. This may mean testing the air for asbestos levels. Just because asbestos exists in a home does not necessarily mean that it needs to be removed. As long as the material is not damaged or disturbed, for example by drilling or remodeling, the fibers will not be released into the air. If asbestos needs to be

removed from your home, you should hire a qualified contractor to do this to avoid contaminating your home or causing any exposure to your family or to the workers. You should not attempt to remove asbestos-containing material yourself.

Asbestos can also be found in some commercial and public buildings (including some schools), where the same basic principles apply. Intact, undisturbed materials containing asbestos generally do not pose a health risk. They may pose a risk if they are damaged, are disturbed in some way, or deteriorate over time and release asbestos fibers into the air. By federal law, all schools are required to inspect materials with asbestos regularly and to have a plan in place for managing them.